Women who experience premature menopause face a significantly higher long-term risk of coronary heart disease, according to a major study published in JAMA. The research, which followed over 10,000 Black and white women in the U.S. for decades, found that those with premature menopause had a 40% increased risk of developing coronary heart disease compared to those who experienced menopause at the typical age.
The study, led by researchers from institutions including Northwestern University, is one of the first to examine the link between premature menopause and lifetime coronary heart disease risk. Premature menopause is defined as occurring before the age of 40, while early menopause occurs between ages 40 and 44.
The elevated risk is believed to be linked to the decline in estrogen, a hormone that offers protective benefits for heart health. The findings underscore the importance of considering a woman's reproductive history as a key factor in assessing her cardiovascular risk profile.
Experts suggest that women who experience premature or early menopause should work closely with their healthcare providers to monitor and manage heart disease risk factors, such as blood pressure and cholesterol, through lifestyle changes and potential medical interventions.
