Venture capitalist Marc Andreessen has publicly stated he has no intention of participating in the growing trend of psychedelic use within Silicon Valley's tech circles. Speaking on the "Founders" podcast hosted by David Senra, the co-founder of Andreessen Horowitz cited hearing numerous stories about such experiences as a reason for his personal disinterest.
"I've heard enough stories," Andreessen said, according to a verified transcript and audio of the episode published in March 2026. He elaborated that these anecdotes, often involving substances like ayahuasca or psilocybin, were sufficient for him to conclude the practice was not for him, without needing a personal trial.
The discussion highlights a cultural divide in the tech industry, where some executives and founders have openly endorsed psychedelics for creativity and mental health, while others remain skeptical. Andreessen's comments reflect a cautious, observational stance rather than a moral condemnation of the trend.
Andreessen Horowitz, a leading venture firm, has invested in mental health and biotechnology companies, but Andreessen's personal remarks distance him from the direct use of psychedelic substances that some of his peers have explored.
